The highway runs somewhat parallel to the Minnesota border to the east and passes through two major cities, Fargo and Grand Forks. The other is from exit 203 to the Canadian border. The first such overlap begins in Watertown, South Dakota, across the state line to Manvel. The highway runs concurrently twice with U.S. Interstate 29 ( I-29) in the US state of North Dakota runs from the state's southern border with South Dakota near Hankinson to the Canadian border just north of Pembina. Richland, Cass, Traill, Grand Forks, Walsh, Pembina
PTH 75 at the Pembina–Emerson Border Crossing
